The Impact of Genomics Evolution and Genomic Island in Burkholderia pseudomallei

Submit Manuscript | http://medcraveonline.com B .pseudomalleus is capable of infecting almost anything because of the spectacular genetic structure, by possessing certain genomic island (GIs) that gives the ability to alteration and to adapt. The genes of this GIs play an important role in pathogenesis ability. Trains which cause disease in humans differ from those causing disease in other animals, Genes on these genomic islands may thus play an important role in the pathogenesis of human melioidosis. It may have the ability to cause disease in humans because of DNA it has acquired from other microorganisms [5]. Its mutation rate is also high, and the organism continues to evolve even after infecting a host [6]. These genetic alterations were primarily driven by environmental pressures outside the human or mammalian host [7].